Some mental health medicines (antipsychotics) can cause abnormal dopamine signaling in the brain. This abnormal signaling can lead to uncontrollable body movements called tardive dyskinesia (TD).
Current research suggests that INGREZZA helps by correcting this abnormal dopamine signaling; however, how INGREZZA works to treat TD is not fully understood.
Dopamine is a chemical in the brain that helps control movement.
TD may be caused by too much dopamine signaling in the brain.
INGREZZA selectively and specifically targets VMAT2,‖ a protein that aids in the release of dopamine…
…which is believed to reduce this abnormal dopamine signaling.
What makes INGREZZA different?Unlike other TD medications, INGREZZA selectively and specifically targets a protein called VMAT2.* VMAT2 aids in the release of dopamine.
*Based on laboratory tests. This does not imply a treatment advantage.
Learn more about what makes INGREZZA different. Sign up for infoActor portrayal With INGREZZA, you can keep takING most mental health medicines.
In a clinical study, psychiatric status remained stable overall in people taking INGREZZA for TD, including those who were also taking medicine for:
Depression Bipolar disorder Schizophrenia Schizoaffective disorderFor questions about INGREZZA, call 1-84-INGREZZA (1-844-647-3992)
Want to know more about INGREZZA and how it works?
Sign up for info Did you know? TD is unlikely to get better on its own. So, it’s important to take control and talk to your healthcare provider about treatment.People taking INGREZZA for TD can stay on their current dose of most mental health medicines.
Watch Carnie Wilson uncover inspirING stories from the TD community
ConnectING with Carnie Carnie Wilson is a paid spokesperson for INGREZZA/Neurocrine Biosciences, Inc. She is not diagnosed with tardive dyskinesia (TD) and does not take INGREZZA.INGREZZA is a treatment that's always one capsule, once daily, and #1 prescribed.
Learn about taking INGREZZA You’re not alone in talking about tardive dyskinesia (TD)Thousands of people he already taken the first step toward talking with their healthcare provider about TD. Within the last year,†‖*‡ the Doctor Discussion Guide has been downloaded over 4000 times, helping people feel more prepared and supported during this important conversation.
Complete the Discussion Guide†‖*‡Source: Google Analytics 4. January 1, 2025–August 31, 2025.
Actor portrayals You are not alone—help may be closer than you thinkThere are over 25,000 neurologists, psychiatrists, and advanced-practice healthcare providers who he experience in discussing TD diagnosis and treatment.‡†
Find a specialist‡†Data on file; 08/2025. Neurocrine Biosciences, Inc.